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The Phototoxicology (PHOT) Module is based on observed rates of
degradation due to sunlight as a factor in determining shelf life of
pharmaceutical products. This module contains information related to 1193
metabolic transformation reactions.
PHOT module can work with two version of the program:
 | META - The
program runs on Alpha Open VMS computers. |
| METAPC -The program runs on Windows 9X/NT/2000 computers. |
Please contact us for prices.
References
Biodegradation
- Klopman, G., Wang, S., and Balthasar, D. M. (1992). Estimation of queous
Solubility of Organic Molecules by the Group Contribution Approach.
Application to the Study of Biodegradation. J. Comp. Chem., 32, 474-482.
- Pangrekar, J., Klopman, G., and Rosenkranz, H. S. (1994). Expert-System
Comparison of Structural Determinants of Chemical Toxicity to Environmental
Bacteria. Environmental Toxicology and Chemistry, 13(6), 979-1001.
- Sedykh A, Saiakhov R, Klopman G. META V.
A model of photodegradation for the prediction of photoproducts of chemicals
under natural-like conditions CHEMOSPHERE 2001, 45(6-7) 971-981
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